The University of Mary Washington researched the efficacy of CELLECT™ in brain tissue and inflammation relative to Alzheimer's Disease and published their findings with the Virginia Academy of Sciences.
A PDF document can be found on the Virginia Academy of Science page. The article is located on page 24 of the PDF document (labeled page 26).
The information presented here is from this document. All formatting and emphasis are done to make reading easier and to highlight important points.
They did the research using mice. After 7 months, the inflammation reduced tremendously and the toxicity was basically non-existent.
Their experiment found that CELLECT™ showed over Eleven Million percent improvement (11,100,000 %).
These findings may also relate to other brain related biochemistry and physiological effects in the body as well.
ABSTRACTS OF PAPERS, 84th Annual Meeting of the Virginia Academy of Science
May 25-26, 2006,
Virginia Polytechnic Institute and State University, Blacksburg, VA
THE EFFECT OF ANTIOXIDANT VITAMINS AND NSAID DRUGS
ON PLAQUE FORMATION IN ALZHEIMER'S DISEASE.
Kristen M. Zach &
Deborah A. O'Dell. Dept. of Biological sciences, Univ. Mary Washington,
Fredericksburg, VA. 22401.
Alzheimer's Disease (AD) is characterized by the
deposition of neurofibrillary tangles (NFTs), neuritic plaques composed of β-
amyloid, the release of inflammatory molecules such as TNF-α", and severe lipid
peroxidation. Although the exact mechanism responsible for causing this cascade
of events is unclear, it is clear that they are interrelated and act synergistically to
cause neuronal death. Recent therapeutic strategies attempt to limit the
neurotoxicitiy of oxidative and immune responses through the use of antioxidant
vitamins and non-steroidal anti-inflammatory drugs (NSAIDs).
To determine the
efficacy of Cellect brand vitamins and Ibuprofen in performing this role, we fed
mice predisposed to plaque development (J10, JAX), rodent chow supplemented
with either vitamins, Ibuprofen, or both for either 4 or 7 months. Mice from two
litters were sacrificed and their brains removed and analyzed for presence of
inflammation (TNF-α) and β-amyloid protein. The level of TNF-α" in mice treated
with supplements for 7 months was much lower than that of the control (0.046
ng/mg tissue vs 5113.38 ng/mg tissue, respectively). Analysis using light
microscopy revealed that mice treated with a combination of Ibuprofen and
vitamins for 7 months had the least amount of β-amyloid protein in the brain. This
study indicates that a long-term diet supplemented with both vitamins and NSAIDs
may help prevent the onset of the hallmark pathologies associated with AD. This
work was supported by an Undergraduate Research Grant from the University of
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Our Notes: Cellect effectiveness against neurotoxicity and immune responses reduced the plaque development.
After 7 months, the presence of inflammation was reduced from 5113.38 down to 0.046
5113.38/ 0.046 = 111,160.43 = 11,116,043 % improvement